It was not the Thanksgiving the Eagles had hoped for as the team was defeated by the Lions, 45-14, in Detroit on Thursday afternoon. Here are some of the biggest takeaways from the Week 12 matchup ...

Injuries Continue To Pile Up

At the 11:26 mark of the first quarter, left tackle Jason Peters went down after a Detroit player fell awkwardly on his left ankle. He was able to walk off the field on his own, but did not return to action.

Early in the second quarter, cornerback Nolan Carroll had his leg rolled up on while defending an outside run. He was carted off the field, and rookie Eric Rowe was inserted into the base defense in his place. The Eagles announced later in quarter that he would not return, and he was taken in for X-rays on his right ankle. But in the third quarter, it was announced that he'd suffered a broken ankle.

Then in another bit of bad news on the injury front for the team, Josh Huff was taken to the locker room during the third quarter to be evaluated for a concussion.

Sanchez Gets The Start

Quarterback Mark Sanchez recorded his second start of the season on Thursday. During the game, he went 19-of-27 for 199 yards, two touchdowns and no interceptions. He was sacked six times and hit a total of nine. Defensive end Ezekiel Ansah had a career-high 3.5 sacks.

Eagles Struggle In The Run Game

Ryan Mathews was sidelined due to a concussion and groin injury, so once again DeMarco Murray was the focal point of the rushing attack for the Eagles. Murray was held to 30 yards on 14 carries, a 2.1 yards per carry average. His longest run was a 19-yard gain. Kenjon Barner rotated in and had 30 yards on seven carries late in the game.

Stafford On Point

After being held without a passing touchdown last week against the Raiders, Lions quarterback Matthew Stafford threw for five touchdowns with no interceptions. He completed 27 of his 38 pass attempts for 337 yards, hooking up with three different receivers for touchdowns on the afternoon.

Calvin Johnson's Career Day

Detroit's Calvin Johnson was the target on one of Stafford's three touchdown passes in the first half, and in the third quarter he caught two more. He finished the day with eight catches for 93 yards and three touchdowns, which tied a career high.

It was not the Thanksgiving the Eagles had hoped for as the team was defeated by the Lions, 45-14, in Detroit on Thursday afternoon. Here are some of the biggest takeaways from the Week 12 matchup …

Injuries Continue To Pile Up

At the 11:26 mark of the first quarter, left tackle Jason Peters went down after a Detroit player fell awkwardly on his left ankle. He was able to walk off the field on his own but did not return to action.

Early in the second quarter, cornerback Nolan Carroll had his leg rolled up on while defending an outside run. He was carted off the field, and rookie Eric Rowe was inserted into the base defense in his place. The Eagles announced later in quarter that he would not return, and he was taken in for X-rays on his right ankle. But in the third, it was announced that he'd suffered a broken ankle.

Then in another bit of bad news on the injury front for the team, Josh Huff was taken to the locker room during the third quarter to be evaluated for a concussion.

Sanchez Gets The Start

Quarterback Mark Sanchez recorded his second start of the season on Thursday. During the game, he went 19-of-27 for 199 yards, two touchdowns and no interceptions.

Stafford On Point

After being held without a passing touchdown last week against the Raiders, Lions quarterback Matthew Stafford threw for five touchdowns with no interceptions. He completed 27 of his 38 passes for 337 yards, hooking up with three different receivers for touchdowns on the afternoon.

Calvin Johnson's Career Day

Detroit's Calvin Johnson was the target on one of Stafford's three touchdown passes in the first half, and in the third quarter he caught two more. He finished the day with eight catches for 93 yards and three touchdowns.